TB-500:
Everything You NEED To Know
What is TB-500?
TB-500 is a peptide used for wound healing and regeneration of muscles, tendons, and ligaments. It is the synthetic and more potent version of the naturally occurring protein Thymosin Beta-4 (Tβ4). Tβ4 is present in almost all cells and plays a key role in healing and regeneration.
Benefits of TB-500
- Accelerated Wound Healing: TB-500 can work wonders especially for healing muscles, tendons, and ligaments, as it promotes angiogenesis, cell migration, and actin upregulation.
- Anti-inflammatory: TB-500 has anti-inflammatory properties, which contributes to improved regeneration and pain relief.
- Scar Reduction: It increases tissue flexibility, reducing the likelihood of scar formation in superficial injuries or skin wounds.
- Better Heart Health: It shows promising results in regenerating damaged heart tissue, and TB-500 improves blood circulation through angiogenesis, potentially reducing the risk of cardiovascular diseases.
- Improved Recovery: TB-500 enables athletes to recover faster.
How does TB-500 work?
TB-500 works through several mechanisms that support the healing process and regeneration in the body.
1. Angiogenesis
TB-500 promotes angiogenesis. Angiogenesis is the process responsible for forming new blood vessels. This process is very important in healing as improved blood circulation brings more oxygen and nutrients to the injury, joint, or bone.
2. Cell Migration
In cell migration, particularly fibroblasts and endothelial cells migrate to the injured area. Fibroblasts are essential for regenerating injured tissue. Fibroblasts are activated during tissue damage and move to the wound area, where they create a new extracellular matrix to restore the damaged tissue. The connective tissue receives structure through this matrix. Endothelial cells, in turn, are crucial for angiogenesis (new blood vessel formation) as they form the innermost cell layer of blood vessels.
3. Increased Collagen Production
Collagen is an essential component of connective tissue. Collagen fibers make connective tissue more resistant. It also strengthens joints, bones, muscles, tendons, and ligaments.
4. Actin Upregulation
Actin is a protein that promotes the previously described angiogenesis (formation of new blood vessels) and cell migration. TB-500 increases actin production, leading to faster regeneration and wound healing.
What are the side effects of TB-500?
Mild common side effects
- Headaches
- Nausea & Dizziness
- Fatigue
- Injection site reactions such as redness or itching
It is advisable to consult a doctor or specialist before use to learn about the legal aspects and health risks.
Is TB-500 legal?
Is TB-500 legal in Germany?
No, Thymosin-beta-4 and its derivatives such as TB-500 fall under the Anti-Doping Law (AntiDopG) in Germany [R].
When purchasing TB-500, the "nicht geringe Menge" should be considered. The "nicht geringe Menge" determines between personal use and criminal behavior such as trading or distributing TB-500. According to the Doping Substance Quantity Regulation (DmMV), the "not insignificant amount" for TB-500 is 100mg [R].
Is TB-500 prohibited by the World Anti-Doping Agency (WADA)?
TB-500 is listed under "S2.3. growth factors and growth factor modulators" on the World Anti-Doping Agency (WADA) prohibited list [R]. Therefore, testing positive in competition could result in disqualification or even suspension.
TB-500 Stacks
TB-500 can be combined with other PEDs to maximize its effects. TB-500 is often taken with BPC-157. Below you'll learn everything you need to know.
Can you stack TB-500 with BPC-157?
Yes, TB-500 is often combined with BPC-157. BPC-157 is also known as the "Wolverine peptide." Similar to TB-500, BPC-157 also has wound healing properties. It is anti-inflammatory, supports angiogenesis and cell migration. The synergistic effect of both peptides can significantly accelerate wound healing.
Many users report extremely accelerated wound healing when taking both peptides together. This could make this stack particularly interesting for healing sports injuries.
Forms of TB-500
TB-500 can be taken in various ways. The probably most popular variant is intake through injection. This method enables rapid and direct absorption into the bloodstream, allowing TB-500 to work most efficiently.
Optionally, TB-500 is also available in patch or capsule form. This could be particularly interesting for people who fear needles. Unfortunately, efficacy and bioavailability are lower.
How to Store TB-500
TB-500 in powder form can be stored at room temperature for days to weeks. If you want to store TB-500 for longer, you should put the peptide in the freezer, ideally at -20°C or -4°F.
TB-500 in liquid form should be stored in a dry, cold, and dark place. The refrigerator is perfect for this. The perfect temperature for storing already reconstituted peptides is 4°C or 39°F.
Frequently Asked Questions
What are other names for TB-500?
Other names for TB-500 are Fx Peptide and Thymosin Beta-4 (Tβ4).
What is the detection time of TB-500?
The detection time of TB-500 is not fully researched. A recent study in rats shows that TB-500 itself is metabolized relatively quickly, but a metabolite (Ac-LKK) can still be detected up to 72 hours after administration [R].
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